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S-Nitrosoglutathione
S-Nitrosoglutathione
- 酸化ストレス関連試薬
NO検出関連試薬
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製品コードN415 S-Nitrosoglutathione
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CAS番号57564-91-7
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化学名N-(N-L-γ-Glutamyl-S-nitroso-L-cysteinyl)glycine
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分子式・分子量C10H16N4O7S=336.32
| 容 量 | メーカー希望 小売価格 |
富士フイルム 和光純薬 |
|---|---|---|
| 25 mg | ￥17,400 | 347-07361 |
| 100 mg | ￥40,400 | 343-07363 |
- ご購入方法
- お問い合わせ
技術情報
溶解例
25 mg/mL（水）、10 mg/mL（ジメチルスルホキシド）
参考文献
1) A. Gibson, R. Babbedge, S. R. Brave, S. L. Hart, A. J. Hobbs, J. F. Tucker, P. Wallace and P. K. Moore, "An Investigation of Some S-Nitrosothiols, and of Hydroxy-arginine, on the Mouse Anococcygeus", Br. J. Pharmacol., 1992, 107, 715.
2) M. W. Radomski, D. D. Rees, A. Dutra and S. Moncada, "S-Nitroso-glutathione Inhibits Platelet Activation in Vitro and in Vivo", Br. J. Pharmacol., 1992, 107, 745.
3) R. M. Clancy and S. B. Abramson, "Novel Synthesis of S-Nitrosoglutathione and Degradation by Human Neutrophils", Anal. Biochem., 1992, 204, 365.
4) J.-W. Park, G. E. Billman and G. E. Means, "Transnitrosation as a Predominant Mechanism in the Hypotensive Effect of S-Nitrosoglutathione", Biochem. Mol. Biol. Int., 1993, 30(5), 885.
5) D. Barrachina, S. Calatayud, J. Esplugues, Brendan J. R. Whittle, S. Moncada and J. V. Esplugues, "Nitric Oxide Donors Preferencially Inhibit Neuronally Mediated Rat Gastric Acid Secretion", Eur. J. Pharmacol., 1994, 262, 181.
6) E. A. Konorev, M. M. Tarpey, J. Joseph, J. E. Baker and B. Kalyanaraman, "S-Nitrosoglutathione Improves Functional Recovery in the Isolated Rat Heart After Cardioplegic Ischemic Arrest-evidence for a Cardioprotective Effect of Nitric Oxide", J. Pharmacol. Exp. Ther., 1995, 274(1), 200.
7) S. C. Askew, D. J. Banett, J. McAninly and D. L. H. Williams, "Catalysis by Cu2+ of Nitric Oxide Release from S-Nitrosothiols (RSNO)", J. Chem. Soc. Perkin Trans.2, 1995, 741.
8) D. J. Banett, A. Rios and D. L. H. Williams, "NO-group Transfer(Transnitrosation) between S-Nitrosothiols and Thiols. Part 2", J. Chem. Soc. Perkin Trans.2, 1995, 1279.
9) J. G. D. Man, B. Y. De. Winter, G. E. Boeckxstaens, A. G. Herman and P. A. Pelckmans, "Effect of Cu2+ on Relaxations to the Nitrergic Neurotransmitter, NO and S-Nitrosothiols in the Rat Gastric Fundus", Br. J. Pharmacol., 1996, 119(5), 990.
10) A. P Dicks and D. L. H. Williams, "Generation of Nitric Oxide from S-Nitrosothiols Using Protein-bound Cu2+ Sources", Chem. Biol., 1996, 3, 655.
11) J. A. Cook, S. Y. Kim, D. Teague, M. Murali, C. Krishna, R. Pacelli, A. M. Miles, M. B. Grisham and D. A. Wink, "Convenient Colorimetric and Fluorometric Assays for S-Nitrosothiols", Anal. Biochem., 1996, 238, 150.
12) 赤池孝章, "ニトロソチオールの検出法", Dojin News, 1997, 84, 11.
13) S. X. L. Liu, Bo Xuan, Z. Chen, R. S. Varma and G. C. Y. Chiou, "Nitric Oxide Donors: Effects of S-Nitrosoglutathione and 4-Phenyl-3-furoxancarbonitrile on Ocular Blood Flow and Retinal Function Recovery", J. Ocul. Pharmacol. Therpeut., 1997, 13(2), 105.
14) C. Alpert, N. Ramdev, D. George and J. Loscalzo, "Detection of S-Nitrosothiols and Other Nitric Oxide Derivatives by Photolysis-chemiluminescence Spectrometry", Anal. Biochem., 1997, 245, 1.
15) T. Akaike, K. Inoue, T. Okamoto, H. Nishino, M. Otagiri, S. Fujii and H. Maeda, "Nanomolar Quantification and Identification of Various Nitrosothiols by High Performance Liquid Chromatography Coupled with Flow Reactors of Metals and Griess Reagent", J. Biochem., 1997, 122, 459.
取扱条件
| 性状： | 本品は、桃色粉末で水、ジメチルスルホキシドに溶ける。 |
|---|---|
| 純度(HPLC)： | 90.0％ 以上 |
| 水溶状： | 試験適合 |
| ジメチルスルホキシド溶状： | 試験適合 |
| 1.保存方法：冷凍 |
