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Trimethylamine N-oxide dihydrate
Applications
- Crystallization grade Trimethylamine N-oxide dihydrate for formulating screens or for optimization
Features
- Sterile filtered solution
- Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
Description
Trimethylamine N-oxide dihydrate
Synonym: TMANO
(CH3)3NO • 2H2O
C3H9NO • 2H2O
Mr 111.14
CAS Number [62637-93-8]
EC Number 214-675-6
Beilstein Registry Number 4(4)144
Merck 14,9711
RTECS YH2850000
MDL Number MFCD00002048
Purity > 98.0%
Maximum solubility is 6.0 M at 25°C (tested by Hampton Research)
Measured pH Range: 8.0 – 9.3 at 25°C
Measured Conductivity Range: 10.9 – 67.1 µS/cm at 25°C
Measured Refractive Index Range: 1.34320 – 1.34348 at 20°C
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CAT NO
HR2-777
NAME
DESCRIPTION
100 mL
PRICE
$130.00
cart quote
Support Material(s)
HR2-777 Trimethylamine N-oxide dihydrate SDS Certificate Of Analysis
References
1. Use of organic cosmotropic solutes to crystallize flexible proteins: Application to T7 RNA polymerase and its complex with the inhibitor T7 lysozyme. Jeruzalmi and Steitz, J. Mol. Bio. (1997) 274, 748-756.
2. Trimethylamine N-oxide as a versatile cryoprotective agent in macromolecular crystallography. Mueller-Dieckmann, C., Kauffmann, B., and Weiss, M. J. Appl. Cryst. (2011). 44, 433–436.
3. Crystallization of a functionally intact Hsc70 chaperone. J. Jiang, E. M. Lafer and R. Sousa. Acta Cryst. (2006). F62, 39-43.
4. Doolittle, R. F. (2003). Biophys. Chem. 100, 307–313.
5. Hill, M. C., Bates, I. R., White, G. F., Hallett, F. R. & Harauz, G. (2002). J.
6. Auton, M. & Bolen, D. W. (2005). Proc. Natl Acad. Sci. USA, 102, 15065–15068.
7. Bolen, D. W. (2004). Methods, 34, 312–322.
Hampton Research, first in crystallization since 1991, developing and delivering crystallization and optimization screens, reagents, plates, and other tools for the crystallization of biological macromolecules, including proteins (antibody), peptides (insulin), and nucleic acids (DNA).
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