Harlan teklad官网动物饲料 Rodent diets 啮齿动物饮食
作为一名研究人员,你想要有尽可能多的控制进入你的研究动物。在恩维戈,我们理解。这就是为什么我们开发了特克拉德全球啮齿动物饮食®.
特克拉德全球啮齿动物饮食®是一个特殊的综合素食实验室啮齿动物的饮食发展为营养完整的各个生命阶段,从繁殖到长期维持。全球啮齿动物实验室饮食中含有更适合现代生物医学研究需要的蛋白质、能量、维生素和矿物质水平。
此外,在全球啮齿类饮食中,人们特别注意尽可能避免使用据报对实验结果产生不利影响的成分。这导致了一系列特克拉德啮齿动物实验室饮食,其中包括:
- 无鱼粉
- 无肉食或肉类副产品
- 无苜蓿粉
- 不含豆粕或降低水平
- 无动物脂肪
通过排除动物副产品,避免了亚硝胺(一种潜在的致癌物)的存在.紫花苜蓿粉的排除降低了叶绿素,提高光学成像清晰度。减少或去除豆粕,加上消除紫花苜蓿粉,可使自然产生的植物雌激素水平降至最低。植物雌激素与内源性雌激素相互作用,可能对许多研究产生影响。研究领域。在以下几篇文章中可以了解更多关于这一点的内容:
- 膳食植物雌激素-一种研究变异的来源
问营养学家系列:植物雌激素对研究的影响,第1卷 - 植物雌激素限制了临床前结果与临床结果的转换
问营养学家系列:植物雌激素对研究的影响,第2卷
产品 | |||
---|---|---|---|
特克勒德啮齿类食物 | 不可蒸压式 | 高压釜 | 辐照 |
总蛋白14% | 2014年c | 2014年s | 2914 |
总蛋白16% | 2016年c | 2016年s | 2916 |
Teklead全局18%蛋白 | 2018年c | 2018S,2018SX | 2918 |
TKLAD全局19%蛋白挤出 | 2019 | 2019 S | 2919 |
全无大豆蛋白挤出 | 2020 X | 2020 SX | 2920 X |
传统饮食 | 见更多 | ||
并不是所有的产品都是在当地库存的,可能需要延长交货期和额外的费用。 许多饮食都是由符合产品代码的“C”指定的认证格式提供的。当饮食被认证时,一个有代表性的样本会被测试一组污染物。如果没有经过认证的库存,可以根据要求提供认证。可适用最低订货量和附加费用。 |
传统的啮齿动物饮食是在几十年前根据对啮齿动物的营养、成分和当时的饮食制造的理解而制定的。虽然传统的饮食将提供已知的您的实验室动物的营养需求,我们建议您考虑使用我们的新的全球饮食线的饮食,以满足您的现代研究需要。
特克拉德全球啮齿动物饮食®现代公式旨在减少研究变量。具体来说,这些饮食含有更合适的营养水平,限制或排除据报道对各种研究终点有影响的成分。
特克勒德啮齿动物饮食是一种特殊的天然成分饮食,旨在提供所有已知营养的适当平衡,这些营养素被认为对老鼠、沙土鼠和仓鼠的生长、维持和繁殖至关重要。这些饮食符合国家研究委员会对啮齿类动物的营养要求(1995年)。
特克拉德啮齿动物的饮食提供了统一的营养。它们是一种固定的配方奶饮食,旨在尽量减少营养差异,否则,如果一种饮食的成分组成从一批改变到下一批,就会发生这种变化。
蛋白质主要由植物来源提供。补充氨基酸是为了提供适当的数量和平衡的必需氨基酸。所有啮齿动物的饮食都含有维生素和矿物质,以帮助支持体液的调节和身体系统的正常运作,以确保研究鼠的充分生长、维持和繁殖。可蒸压饮食补充维生素,以弥补在高压灭菌过程中发生的损失。由于我们的饮食是营养完整和平衡的,所以没有必要添加膳食补充剂。
没有一个确定的点,人们能够预测什么时候一个特定的饮食会变质或变得缺乏一个或多个营养。六个月保质期的共同准则是以北美长期的实践为基础的。在欧洲和亚洲,当地做法和监管监督方面的差异导致特克拉德标准天然成分饮食被例行使用到9个月,有时甚至在生产后12个月。这种实践经验,随着时间的推移,再加上文献支持和维生素测试,让我们相信,这些饮食继续支持动物的健康和研究的完整性,至少在9个月后生产。如果你不确定当地的政策,请向你的机构寻求指导。
建议的储存条件:
- 凉爽和干燥;在华氏70度或以下,湿度最好在50%以下,但高达65%是可以接受的。
- 清洁无害虫
- 在原始包装中或容器中,防止连续暴露于光线下,并将空气暴露在最小范围内。
标准的天然成分啮齿类食物是大鼠、老鼠、沙土鼠和仓鼠的完整饮食,这是应该允许的。[医]锂节食的机会。任何时候都应该有淡水供应。
As a researcher, you want to have as much control as possible over what goes into your study animals. At Envigo, we understand that. That is why we developed Teklad Global Rodent Diets®.
Teklad Global Rodent Diets® are a special integrated range of vegetarian laboratory rodent diets developed to be nutritionally complete for various life stages from breeding through long-term maintenance. Global rodent laboratory diets contain levels of protein, energy, vitamins and minerals that are more appropriate to the needs of modern biomedical research studies.
Furthermore, in global rodent diets particular attention has been placed on avoiding, as far as practical, ingredients that are reported to have adverse confounding effects on experimental results. This has resulted in a range of Teklad rodent laboratory diets that contain:
- No fish meal
- No meat meals or meat by-products
- No alfalfa meal
- No soybean meal or reduced levels
- No animal fat
By excluding animal by-products, the presence of nitrosamines (a potential carcinogen) is avoided. Exclusion of alfalfa meal reduces chlorophyll, improving optical imaging clarity. Reduction or removal of soybean meal, together with elimination of alfalfa meal, minimizes levels of naturally-occurring phytoestrogens. Phytoestrogens interact with endogenous estrogens and potentially can affect studies in many research areas. Read more about this in these pieces:
- Dietary phytoestrogens, a source of research variation
Ask a Nutritionist Series: Impact of phytoestrogens on research, Volume 1 - Phytoestrogens limit translation of preclinical results to clinical outcomes
Ask a Nutritionist Series: Impact of phytoestrogens on research, Volume 2
Products | |||
---|---|---|---|
Teklad rodent diets | Non-autoclavable form | Autoclavable | Irradiated |
Teklad global 14% protein | 2014, 2014C | 2014S | 2914 |
Teklad global 16% protein | 2016, 2016C | 2016S | 2916 |
Teklad global 18% protein | 2018, 2018C | 2018S, 2018SX | 2918 |
Teklad global 19% protein extruded | 2019 | 2019S | 2919 |
Teklad global soy protein-free extruded | 2020X | 2020SX | 2920X |
Traditional diets | see more | ||
Not all products are stocked locally; extended lead time and additional fees may apply. Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply. |
Traditional rodent diets were formulated decades ago based on understanding of rodent nutrition, ingredients, and diet manufacturing at the time. While traditional diets will supply the known nutrient needs of your laboratory animals, we recommend you consider the use of a diet from our newer global diet line for your modern research needs.
Teklad Global Rodent Diets® are modern formulas designed to reduce research variables. Specifically, these diets contain more appropriate nutrient levels, and limit or exclude ingredients that are reported to have effects on a wide variety of research endpoints.
- Lower, more appropriate protein levels can improve survival and reduce morbidity
- Vegetarian with no nitrosamines (a potential carcinogen)
- Formulated to exclude alfalfa meal, greatly improving fluorescent imaging clarity
- Formulated to exclude or lower soybean meal, thus minimizing the presence of isoflavones, the primary type of phytoestrogen found in lab animal diets
- Extruded rodent diets dramatically reduce clumping and hardness after autoclaving (2018SX, 2019S, 2020SX), and in general result in less diet waste and cleaner cages
Teklad rodent diets are natural-ingredient diets specifically formulated to provide the proper balance of all known nutrients considered essential for the growth, maintenance, and reproduction of rats, mice, gerbils and hamsters. These diets conform to the nutrient requirements for rodents established by the National Research Council (1995).
Teklad rodent diets provide uniform nutrition. They are fixed-formula diets designed to minimize the nutrient variances which otherwise could occur if the ingredient composition of a diet were altered from one batch to the next.
Protein is supplied primarily by plant sources. Supplemental amino acids are added to provide the proper amount and balance of essential amino acids. All rodent diets are fortified with vitamins and minerals to help support the regulation of body fluids and the proper functioning of body systems to ensure the adequate growth, maintenance, and reproduction of research rodents. Autoclavable diets are supplemented with additional vitamins to compensate for losses that occur during autoclaving. Since our diets are nutritionally complete and balanced, it is not necessary to add dietary supplements.
There is no definitive point where one is able to predict when a specific diet will spoil or become deficient in one or more nutrients. The common guideline of a six month shelf life is based on longstanding practice in North America. In Europe and Asia, differences in local practices and regulatory oversight have led to Teklad standard natural ingredient diets being routinely used out to nine months and sometimes 12 months post-manufacture. This practical experience, along with literature support and vitamin testing over time, gives us confidence that these diets continue to support animal health and study integrity out to at least nine months post-manufacture. Please refer to your institution for guidance if you are unsure of local policies.
Recommended storage conditions:
- Cool and dry; at or below 70 degrees fahrenheit with humidity ideally below 50%, but up to 65% is acceptable
- Clean and free of pests
- In original packaging or in a container that prevents continuous exposure to light and minimal exposure to air
Standard natural ingredient rodent diets are complete diets for rats, mice, gerbils and hamsters, that should be allowed ad libitum access to the diet. Fresh water should be available at all times.